Coronary artery stenosis is a medical condition characterized by the progressive narrowing of the coronary arteries, vital vessels responsible for supplying the heart muscle with oxygenated blood. The constriction results from the accumulation of plaque—a mixture of fatty deposits, cholesterol, and other substances—along the inner walls of these arteries. As this plaque builds up over time, it impedes the normal blood flow to the heart, leading to a reduction in the delivery of essential oxygen and nutrients to the cardiac muscles. The consequence of this diminished blood supply may manifest as chest pain or angina, and in severe instances, it can precipitate a heart attack. This condition is intricately linked with atherosclerosis, a persistent inflammatory condition affecting arteries throughout the body. Lifestyle choices, including a suboptimal diet, insufficient physical activity, and smoking, along with genetic factors, collectively contribute to the development of coronary artery stenosis.
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