For years aspirin was considered an essential part of the treatment of patients with or at risk of coronary artery disease. However, more recent studies have shown that aspirin, even at low dose, does not improve outcomes when administered for primary prevention and is associated [....] » Read More
Congenital heart disease is one of the more common congenital anomalies with an incidence of approximately 4 per 1000 live births. Although many of these infants are born at term with birthweights well within the normal range, they often can develop growth failure due to in [....] » Read More
In the first decades of the 21st century, chronic noncommunicable diseases (CNCDs) remain the leading cause of disability and death among adults in the developed world. Their total share in mortality is about 77%. Malignant oncological diseases, along with cardiovascular diseases [....] » Read More
Background:The clinical presentation of viral myocarditis is variable and is an important cause of cardiomyopathy worldwide. In some cases, symptoms are minimal consisting of mild fatigue and chest discomfort, where other cases result in fulminant heart failure, arrythmia and sud [....] » Read More
BACKGROUND There are a multitude of barriers that can lead to poor cardiac outcomes in the United States, especially those faced by underrepresented and minority populations. The development of new advancements in the field of Artificial Intelligence has become a primary tool in [....] » Read More
Background:Myopericarditis is a rare complication of the mRNA Covid-19 vaccines, and often affects young males. We present a case of myopericarditis in a 68-year-old male with AML after receiving the 2nd booster (4th dose) of mRNA-1273 (Moderna booster). Case:A 68-year-old mal [....] » Read More
Risk factors for sudden cardiac death (SCD) and prevention guideline Incidence of SCD Review of SCD risk factors Risk factor reduction treatment Prevention guidelines Defibrillator (ICD) guidelines - USA
Cardiovascular disease is the leading cause of mortality for women and is responsible for 35% of total deaths in women, since there is a growing interest (as the Lancet Commission alert) on reducing the global burden of cardiovascular disease. It is estimated that obesity contrib [....] » Read More
Animals are an important tool for studying human diseases. Our research team has used rodents as models of metabolic and oncological diseases, like diabetes and prostate, mammary, colon, liver, and urinary bladder cancers. In our experiments, we have monitored the cardi [....] » Read More
Introduction: Cardiac fibrosis is an event characterized by an increased collagen type I deposition due by cardiac fibroblast activation and differentiation into myofibroblasts, that cause abnormalities in cardiac function. Replacement fibrosis occurs after cardiac injury like my [....] » Read More
Background: Patients with familial hypercholesterolemia (FH) are at risk of premature myocardial infarction (PMI) and thus benefit from screening programs for causal gene mutations and preventive management. The scarce of data about LDLR gene mutation frequency in Vietnames [....] » Read More
Patient presentation: A 73-year-old male of Irish ethnicity was incidentally found to have a large pericardial effusion on a CT thorax, abdomen, and pelvis (CT-TAP) as part of investigations into a 6-month history of weight loss (11 kg), iron deficiency anaemia and progressive e [....] » Read More
Introduction: Exercise intolerance in patients with heart failure leads to a lower quality of life. An increasing number of studies suggest that early initiation of guided-directed medical therapy (GDMT) leads to better outcomes. Sodium-glucose co-transporter-2 (SG [....] » Read More
Statement of the Problem: Coronary artery ectasia (CAE) or aneurismal coronary artery disease (CAD) is dilatation of an arterial segment to a diameter at least 1.5 times that of the adjacent normal coronary artery. This form of atherosclerotic coronary artery disease (CAD) [....] » Read More
Background Aortic regurgitation changes the loading condition of the aorta, and the changes of the longitudinal strain of the sinus of Valsalva and the ascending aorta remains unclear.The purpose of this study was to evaluate the longitudinal strain of the sinus of Valsalva [....] » Read More
Background: There are few reports of total arch replacement through a partial upper sternotomy in obese patients with type A aortic dissection, and the safety and feasibility of this procedure still need to be further investigated. The present study also sought to investigat [....] » Read More
The risk of cardiovascular disease increases at an alarming rate with the increase in an individual’s blood pressure. Rise in systemic arterial blood pressure can be caused by factors such as unhealthy diet (excessive intake of salts, trans-fats and saturated fats), alcohol [....] » Read More
Objective: To compare the levels of microRNA (miRNA) 24 levels in diabetic patients with acute coronary syndrome (ACS) with non-diabetics suffering from ACS. Methodology: A prospective case-control study was carried out among 40 patients with ACS residing in Belagavi, Karnatak [....] » Read More
Background & Objective The prevalence rate of Hyperuricemia is comparatively higher in Asian countries than in the western regions. Hypertensive patients with co-existing Hyperuricemia (HU) are at greater risk of uncontrolled HTN, metabolic syndrome and its complications. Th [....] » Read More
Every year, about 1.5 million pilgrims visit the 14 km long Kedarnath temple trek on foot at the height of 3584 meters above sea level. In 2022, the months of May and June reported a drastic increase in mortality due to Myocardial infarction in the pilgrims. Hence, a health [....] » Read More
Drugs that have analgesic and antipyretic properties are known as nonsteroidal anti-inflammatory drugs (NSAIDs) in general. It is commonly acknowledged that there is a chance of blood pressure increase and heart failure. The known information on the Cardiovascular risk of NSAIDs, [....] » Read More
Background: Much concern was directed towards studying cardiovascular dysfunction in patients with multiple sclerosis (MS). However, the mechanisms of such dysfunction are not completely elucidated. Aim of the work: The aim of our work was to assess cardiac and arterial function [....] » Read More
One of the most important co-occurring conditions in heart failure is renal dysfunction, and on the other face of the coin, diminished estimated glomerular filtration rate is a prognostic factor of cardiovascular mortality and complications. In 1836 Rober [....] » Read More
Rationale: A novel COVID-19 with a severe acute respiratory syndrome or pneumonia had arisen in Wuhan, China in December 2019. Emerging atrial fibrillation in COVID-19 patients is highly significant in cardiovascular medicine. A newly coronary artery spasm in the presentation of [....] » Read More
Purpose:High levels of coronary artery stenosis (>50%) increases the risk for ischemic heart disease, the leading cause of death worldwide. A novel procedure called intravascular lithotripsy (IVL) can reduce the levels of coronary artery stenosis by disrupting calcified plaque [....] » Read More
Background: Prior studies of internal medicine and emergency medicine residents have reported low confidence in accurately interpreting electrocardiograms (ECG). In 2014, an ECG Reading and Arrhythmia course was developed at the University of Arkansas for Medical Sciences (UAMS) [....] » Read More
A 75-year-old male with hypertension and GERD, who was a lifelong non-smoker, and consumes very little alcohol presented to our service with acute epigastric pain. He complained of intermittent mild nausea for the past 6 months. CT scan of the abdomen & pelvis showed acute pa [....] » Read More
A 27year old female with a history of Roux-en-Y gastric bypass, complicated by gastrojejunal anastomotic stricture resulting in Wernicke’s encephalopathy due to thiamine deficiency was admitted to our service for persistent tachycardia, palpitations, symptomatic orthostatic [....] » Read More
Background: Chest pain in patients with angina and no obstructive coronary artery disease (ANOCA) is a diagnostic and treatment challenge, resulting in a significant burden on healthcare resources. With increasing recognition of ANOCA, it is uncertain if the healthcare resource u [....] » Read More
This presentation summarizes the clinical and radiological characteristics of patients with an anomalous origin of the left circumflex artery from the right sinus of Valsalva (RCx), diagnosed by cardiac computed tomography (CT). This anomaly is a rare type of anomalous aortic ori [....] » Read More
Hoarseness and dysphagia are common presenting symptoms in daily clinical practice seldom associated with cardiovascular disease and yet, these may be the only manifestations of an unknown serious disease. Cardiovocal syndrome, also called Ortner’s syndrome, is a rare clini [....] » Read More
INTRODUCTION: Danon's disease is a dominant mutation linked to the X chromosome that is characterized by the deficiency of a protein that exist in the lysosomal membrane, Lysosome-Associated Membrane Protein 2 (LAMP2). LAMP2 plays an essential role in carrying out autophagy a [....] » Read More
Here I report a rare case of LAD mycotic Aneursym Post PCI which formed a Fistula to PA Audience Takeaway: Infective complications post PCI are rare. My presentation will help the clinicians to prevent future coronary complications I will present the complication of [....] » Read More
Objective: To know the clinical outcomes of percutaneous intervention (PCI) with drug eluting stents (DES) in patients with unprotected left main stem disease. Methodology & Theoretical Orientation: This single-center, prospective, observational study was conducted on 133 pat [....] » Read More
Background: Traumatic brain injury may lead to left ventricular (LV) dysfunction, arrhythmia, and positive cardiac enzymes secondary to adrenergic myocarditis. Aim: To study the evolution of left ventricular ejection fraction (LVEF) in severe Traumatic brain injury patients in t [....] » Read More
Title : A single site experience of implementation of a Gastrostomy Tube (G-Tube) weaning protocol in single ventricle patients
Sarah Watson, Children's Hospital Colorado, United States
Background: Nearly 50% of children with single ventricle physiology require a feeding tube following first stage palliation. Standardization of practice in weaning from feeding tubes has been shown to suppo oral feeding success. Without a standardized method to rei [....] » Read More
Title : Effect of extracardial myocardial revascularization on long-term results of surgical treatment of patients with coronary heart disease
Yuriy Leonidovich Shevchenko, Pirogov National Medical and Surgical Center, Russian Federation
To improve the results of treatment of patients with coronary artery disease (CHD) and diffuse coronary lesion we developed in 2007 and introduced into clinical practice the method of induction of extracardial neoangiogenesis – "YurLeon" (patent for invention of t [....] » Read More
Title : Between the brain and the heart: Effects of reward system activation on the recovery process following myocardial infarction
Hedva Haykin, Technion- Institute of Technology, Israel
Background: Epidemiological data show a correlation between negative emotional states, such as depression and stress, to a higher incidence of acute cardiovascular events like myocardial infarction (MI), with more frequently occurring comorbidities and mortality. Consistent [....] » Read More
Title : The effect of early cardiopulmonary rehabilitation combined with melatonin supplementation in patients with myocardial infarction treated by a primary percutaneous coronary intervention
Mohamed Ali Hbaieb, University of Poitiers, France
Patients with myocardial infarction (MI) treated by a primary percutaneous coronary intervention (PCI) have a decreased functional capacity during inpatient period due to the presence of sleep disturbances caused by the low melatonin secretion and the severe oxidative stress foll [....] » Read More
Title : Heart failure: assessments and treatment prior to and during geriatric care
Marianne Reimers Wessberg, Karolinska Institute, Sweden
Background: Heart failure (HF) is globally the most common cause for admission to hospital for patients 65 years and older in high income countries. Research on HF has however often focused on younger patients. The aim of these studies was to analyze extent of investigation and t [....] » Read More
Title : Prevalence and clinical features of pre-diabetes and diabetes in patients with hypertension
Chang Gyu Park, Korea University, Korea, Democratic People's Republic of
Objective: Although prediabetes/diabetes and hypertension are identified as major risk factors for cardiovascular diseases, no data have been reported on the prevalence and characteristics of prediabetes/diabetes in hypertensive patients. We evaluated the prevalence and character [....] » Read More
Title : Rare case of tuberculous chylopericardium managed conservatively
Kevin Paul Enriquez, Philippine General Hospital, Philippines
Chylopericardium is a rare condition in which there is accumulation of chylous fluid in the pericardial cavity. Commonly it is idiopathic, postoperative, or neoplastic. Tuberculosis (TB) as a cause has infrequently been reported. Optimal management is unclear, being conservative [....] » Read More
Title : A conceptual paper on stakeholder collaboration aimed at addressing the psycho-social needs of women living with hypertension: Community development approach
Linda Shirindi, University of South Africa, South Africa
Stakeholder collaboration is significant to the contribution and improvement of psycho-social functioning and resilience of women living with hypertension. The purpose of the study was to explore and describe perceptions of stakeholders in addressing psycho-social needs of women [....] » Read More
Title : Assessment of strain imaging in the prediction of early cancer therapy-related cardiac dysfunction (CTRCD) troponin and its correlation with serum biomaker (TROPONIN-I)
Dhulipalla Dharma Teja, NRI Medical college, India
Introduction: Cancer therapy-related cardiac dysfunction (CTRCD) is one of the side effects experienced by nearly one-tenth of cancer survivors. LVEF and GLS have been proposed as a marker to predict CTRCD. Recent studies also suggest assessment of cardiac biomarkers including tr [....] » Read More
Title : Assessment on achieving secondary prevention targets after one year of coronary angioplasty; A single center retrospective cohort study from India
Elvis Joseph, Aster Medcity, India
Introduction: Recurrent Major Adverse Cardiovascular Events (MACE) after coronary angioplasty can be significantly reduced by adhering to strict targets of lipids, blood pressure and blood sugar together. Studies are limited on the percentage of post coronary angioplasty patient [....] » Read More
Title : Assessment of risk factors, pattern and severity of CAD in semi-urban Indian women
Shivling Sanjay Swami, Bharti Vidyapeeth Medical college and Hospital, India
Introduction: It is an alarming observation that one third of all women in their fourth decade will develop coronary artery disease(1). Moreover, young women who develop coronary artery disease have a higher morbidity and mortality as compared to men of same age. (1,2) Traditiona [....] » Read More
Title : An unusual case of post-thrombolysis emergency Coronary Artery Bypass Graft surgery(CABG) with postoperative complication of hemothorax in a young patient
Anuja Waidande, Bharti Vidyapeeth Medical college and Hospital, India
We present a case of a 43-year-old man, a known case of hypertension, who was diagnosed with acute myocardial infarction for which he was given streptokinase (Fibrinolytic drug).He presented to the hospital with exertional dyspnoea and chest pain. Angiogram showed triple-vessel d [....] » Read More
Title : Role of intracoronary adenosine in prevention of no reflow guided by MVO by CMR
Ahmed Ibrahim Hatata, Ain Shams University, Egypt
The adenosine is an available drug and the tool is ready for treatment of no reflow but how is the drug is used in prevention of no reflow was the study. In this study we used adenosine as primary intervention for no reflow after establishing TIMI I flow in primary PCI [....] » Read More
Title : Role of intracoronary adenosine on prevention of no reflow during Primary PCI in STEMI patients guided by MVO in CMR
Ahmed Hatata, Ain Shams University, Egypt
Background:Microvascular obstruction (MO) or no-reflow phenomenon is an established complication of coronary reperfusion therapy for acute myocardial infarction. It is increasingly recognized as a poor prognostic indicator and marker of subsequent adverse LV remodeling. Microvasc [....] » Read More
Title : Solutions for physical activity adherence in heart failure patients: A review of reviews
Hossein Karimi Moonaghi, Mashhad University of Medical Sciences, Iran (Islamic Republic of)
Introduction: Despite the importance of physical activity in heart failure treatment, physical activity adherence in HF patients is low. The purpose of this review is to obtain the best strategies for enhancing physical activity adherence among HF patients. Methods: databases [....] » Read More
Title : Assessment of treatment with spironolactone on right ventricular function in patients with type 1 pulmonary hypertension
Yeganeh Mobasser, MUMS, Iran (Islamic Republic of)
Despite evidence showing the effect of vasoactive hormones including aldosterone in pulmonary arterial hypertension (PAH) pathophysiology, few clinical reports are available concerning the effect of PAH treatment with aldosterone antagonists. Therefore, in this study, we evaluate [....] » Read More
Title : Exercise training improves diastolic function in IHD patients.
Nahid Mobasser, ZUMS, Iran (Islamic Republic of)
Purpose: The purpose of this study was to investigate the effect of exercise training on exercise tolerance and left ventricular diastolic function and structure in patients with chronic cardiac ischemia. Methods: Eighty-eight patients with cardiac ischemia and diastolic disfu [....] » Read More
Title : The role of interleukin-2 and 6, and the janus kinase signaling pathways in the treatment of severe SARS-CoV-2 associated myocarditis
Nightingale Syabbalo, Nabanji Medical Center, Zambia
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) is caused by an enveloped, single-stranded RNA betacoronavirus belonging to the corona viridae 2B lineage. Several epidemics of SARS-CoV-2 due to different variants have caused severe morbidities and deaths in [....] » Read More
Title : Wide complex tachycardia: A clinical conundrum: VT versus WPW syndrome
Indrajeet Mahata, University of Missouri, United States
Introduction: The accurate diagnosis and initial evaluation of Wide complex tachycardia (WCT) has been a traditional clinical dilemma. The differential diagnosis includes ventricular tachycardia (VT), supraventricular tachycardia (SVT with aberration and SVT with pre-excitat [....] » Read More
Title : Surgical outcome of post-infarction left ventricular free wall rupture
Chan Young Na, Dontan Hospital, Korea, Democratic People's Republic of
Background and objectives Left ventricular free rupture is rare and one of the fatal complications after acute myocardial infarction. Early recognition and aggressive treatment is recommended. Methods Between August 1999 and February 2023, eleven patients with ages betwe [....] » Read More
Title : Cardiovascular risk biomarkers and grip frailty among newly-diagnosed ART-naive HIV-infected Filipino patients
Ana Joy Lozano, University of the Philippines Manila, Paraguay
Background: People living with HIV in the Philippines are relatively younger compared to western countries. They are then confronted with longer duration of infection and use of antiretroviral therapy (ART) increasing their risk of developing cardiovascular diseases (CVD). Frailt [....] » Read More
Title : Simplified Method for the simultaneous isolation of viable cardiomyocytes and nonmyocytesfrom the adult mouse heart
Mariel Lizbeth Joy Agsaoay, University of the Philippines, Philippines
Cardiovascular diseases (CVDs) have remained the leading cause of global mortality. Of these, one of the main events leading to death is myocardial infarction (MI), followed by cardiac fibrosis. To better understand the disease and its development, various techniques [....] » Read More
Title : Metastudy of potential key genes associated with cardiac fibrosis after acute myocardial infarction from published microarray data in a mouse model
Al James A Manua, University of the Philippines - Diliman, Philippines
In this study, we investigated the shared key genes, pathway networks, and transcription factors (TFs) associated with Cardiac Fibrosis following Acute Myocardial Infarction (AMI) in mouse models. Gene expression profiles of AMI and the sham-control group were obtained from the [....] » Read More
Title : Unmasking of Type-1 Brugada syndrome in a case of Aluminium Phosphide (Celphos) poisoning: An unusual phenomenon
Ishan Verma, AIIMS Nagpur, India
A 21 year old female was brought to the emergency department of our hospital with alleged history of celphos consumption an hour back at home. Following consumption, she had 2 episodes of vomiting. On arrival in the emergency, she was irritable and in gasping condition. Endotrach [....] » Read More
Title : Elevated expression of SORT1 gene in patients with coronary artery disease
Shelly Aggarwal, University of Delhi, India
Background: Background: Genome-wide association studies demonstrate that SORT1 gene expression affects lipid metabolism, identifying it as a risk gene for coronary artery disease (CAD). Sortilin protein enhances low density lipoprotein (LDL) absorption, form cell development, and [....] » Read More
Title : Geriatric cardiology in Nigeria: A necessary discipline?
Aisha Oluwabunmi Ajala, University of port-harcourt teaching hospital, Nigeria
Background Cardiovascular disease (CVD) accounts for the major cause of morbidity and mortality in older adults and occurs amidst several co-morbidities and geriatric syndromes. Nigeria, with the largest growing economy in the continent is not spared by the process of aging of [....] » Read More
Title : The effectiveness of a pain management teaching intervention on post-operative cardiac patients in a tertiary care hospital of Karachi, Pakistan
Sehrish Salim, The Aga Khan University hospital, Pakistan
Background Cardiovascular diseases (CVD) are regarded as a major cause of death worldwide; around 18 million people die annually due to cardiovascular diseases. Most of the patients feel higher intensity of pain during the initial post-operative day and this gradually decreases o [....] » Read More
Title : Furin as a potential biomarker in SARS?CoV?2 infection in patients with Pre-existing cardiometabolic diseases.
Laila Rejali, Islamic Azad University, Iran (Islamic Republic of)
Background: SARS-CoV-2 entry requires cleavage of the spike glycoprotein at the S1/S2 and the S2? cleavage sites to mediate membrane fusion. The furin cleavage site is an important determinant of SARS-CoV-2 transmission. Through proteolytic cleavage of ADAM17, furin also indirect [....] » Read More