In the first decades of the 21st century, chronic noncommunicable diseases (CNCDs) remain the leading cause of disability and death among adults in the developed world. Their total share in mortality is about 77%. Malignant oncological diseases, along with cardiovascular diseases [....] » Read More
Congenital heart disease is one of the more common congenital anomalies with an incidence of approximately 4 per 1000 live births. Although many of these infants are born at term with birthweights well within the normal range, they often can develop growth failure due to in [....] » Read More
Dyslipidaemia comprises of abnormal lipid components and refers mainly to increased levels of LDL, non HDL particles and triglycerides while decreased levels of HDL Dyslipidaemia is a common and independent modifiable risk factor for cardiovascular disease. Be [....] » Read More
Cardiovascular disease is the leading cause of mortality for women and is responsible for 35% of total deaths in women, since there is a growing interest (as the Lancet Commission alert) on reducing the global burden of cardiovascular disease. It is estimated that obesity contrib [....] » Read More
Background: Congenital heart disease (CHD) remains one of the leading causes of infant and postneonatal mortality. Early recognition and successful management of critically ill CHD patients is a difficult challenge considering the complexity of the anatomy and physiopathology of [....] » Read More
Objective: With the help of CiteSpace software platform, a visual analysis was carried out around the literature on the relationship between "hyperuricemia" and "insulin resistance", to explore the relationship between the two, and to summarize and predict the [....] » Read More
Background: Following an acute coronary syndrome (ACS), a patient’s ability to drive might be impaired and the Driver and Vehicle Licensing Agency (DVLA) provides guidance on driving restrictions post-ACS. The medical team is responsible for informing patients of drivi [....] » Read More
Objective: To compare the levels of microRNA (miRNA) 24 levels in diabetic patients with acute coronary syndrome (ACS) with non-diabetics suffering from ACS. Methodology: A prospective case-control study was carried out among 40 patients with ACS residing in Belagavi, Karnatak [....] » Read More
The risk of cardiovascular disease increases at an alarming rate with the increase in an individual’s blood pressure. Rise in systemic arterial blood pressure can be caused by factors such as unhealthy diet (excessive intake of salts, trans-fats and saturated fats), alcohol [....] » Read More
Epicardial adipose tissue is an area of multidisciplinary interest and tremendous potential for upcoming research. It is composed of adipocytes as well as inflammatory cells, nervous cells, vascular cells and immune cells. It has multiple protective functions and has fu [....] » Read More
HIV infection is associated with high rates of Cardiovascular disease complications, including acute myocardial infarction, sudden cardiac death, and heart failure. It has been found that patients with HIV have a 2-fold risk of Cardiovascular disease and 50 percent increased [....] » Read More
Objectives: To investigate the prevalence of obstructive sleep apnea (OSA), anthropometric and clinical characteristics of patients with atrial fibrillation (AF), and assess the possibilities of screening diagnosis for OSA. Materials and Methods: The study involved AF patients ( [....] » Read More
Introduction: Rib fractures are a frequently identified injury in the trauma population. Nonoperative treatment is based on pain control and aggressive supportive pulmonary care primarily aimed at avoiding the need for intubation, which is associated with increased rates of pneum [....] » Read More
Widespread knowledge and awareness of Modifiable Cardiovascular Risk Factors (MCRF) may be essential to reduce the burden of Cardiovascular Diseases (CVD). However, the lack of Doctor-Patient Communication (DPC) about personal Cardiovascular Risk (pCVR) could have negative i [....] » Read More
Premature Atherosclerotic cardiovascular disease (ASCVD) represents a growing challenge that needs more attention to be addressed in early adulthood. It correlates highly with dyslipidaemia, male sex, smoking, inflammatory disease, hypertension, and family history of premature AS [....] » Read More
Despite evidence showing the effect of vasoactive hormones including aldosterone in pulmonary arterial hypertension (PAH) pathophysiology, few clinical reports are available concerning the effect of PAH treatment with aldosterone antagonists. Therefore, in this study, we evaluate [....] » Read More
Purpose: The purpose of this study was to investigate the effect of exercise training on exercise tolerance and left ventricular diastolic function and structure in patients with chronic cardiac ischemia. Methods: Eighty-eight patients with cardiac ischemia and diastolic disfu [....] » Read More
Background:Myopericarditis is a rare complication of the mRNA Covid-19 vaccines, and often affects young males. We present a case of myopericarditis in a 68-year-old male with AML after receiving the 2nd booster (4th dose) of mRNA-1273 (Moderna booster). Case:A 68-year-old mal [....] » Read More
Background: The clinical presentation of viral myocarditis is variable and is an important cause of cardiomyopathy worldwide. In some cases, symptoms are minimal consisting of mild fatigue and chest discomfort, where other cases result in fulminant heart failure, arrythmia and su [....] » Read More
Sudden Cardiac Death (SCD) is one of the leading causes of death world wide. It is caused by ventricular arrhythmias and usually occurs suddenly without much notice. SCD can occur in patients with structural abnormal hearts specifically the patient with left sided systo [....] » Read More
Background: There are a multitude of barriers that can lead to poor cardiac outcomes in the United States, especially those faced by underrepresented and minority populations. The development of new advancements in the field of Artificial Intelligence has become a primary to [....] » Read More
Introduction: Cardiovascular Diseases are responsible for substantial damage to the health system, being the main cause of mortality in the world, just as Pain is the main cause of disability in the world. It is common for individuals diagnosed with both pathologies as well as ot [....] » Read More
Rationale: A novel COVID-19 with a severe acute respiratory syndrome or pneumonia had arisen in Wuhan, China in December 2019. Emerging atrial fibrillation in COVID-19 patients is highly significant in cardiovascular medicine. A newly coronary artery spasm in the presentation of [....] » Read More
a1D-adrenoceptor (a1D-AR) is a G-coupled receptor involved in blood pressure regulation, so far, its activity has been determined using BMY 7378, a drug with high affinity for them; but, with some other therapeutic blanks, as 5HT1 receptors, which could contribute indirectly with [....] » Read More
Atrial fibrillation (AF) is a common arrhythmia characterized by rapid, irregular electrical activity in the atria of the heart. It is associated with significant morbidity and mortality, and its prevalence is increasing worldwide. The major cardiac causes of AF include hypertens [....] » Read More
Introduction Antiphospholipid syndrome (APS) is a disorder of autoimmune system presented clinically by arterial or venous thrombosis. One of the rare and severe forms of APS is known as catastrophic APS (CAPS). The incidence of CAPS has been reported in 0.8% of patients with AP [....] » Read More
Background: Brugada syndrome is a rare diagnosis with a prevalence of 3 to 5 per 10,000, accounting for 4% of all sudden cardiac deaths. It can present with ventricular tachyarrhythmia and sudden cardiac deaths in structurally normal hearts, with an autosomal dominant patter [....] » Read More
Introduction: Sacubitril/valsartan in one of the pillars of fantastic four and has been established as an effective treatment for heart failure (HF) with reduced ejection fraction based on clinical trial data; however, little is known about its use or impact in real-world practic [....] » Read More
This presentation summarizes the clinical and radiological characteristics of patients with an anomalous origin of the left circumflex artery from the right sinus of Valsalva (RCx), diagnosed by cardiac computed tomography (CT). This anomaly is a rare type of anomalous aortic ori [....] » Read More
Purpose:High levels of coronary artery stenosis (>50%) increases the risk for ischemic heart disease, the leading cause of death worldwide. A novel procedure called intravascular lithotripsy (IVL) can reduce the levels of coronary artery stenosis by disrupting calcified plaque [....] » Read More
A 75-year-old male with hypertension and GERD, who was a lifelong non-smoker, and consumes very little alcohol presented to our service with acute epigastric pain. He complained of intermittent mild nausea for the past 6 months. CT scan of the abdomen & pelvis showed acute pa [....] » Read More
One million hospital admissions annually in the United States (US) are due to heart failure, with heart failure being the principal cause of 30-day readmissions. The major health problem with individuals diagnosed with heart failure is its high incidents of hospitalizations and r [....] » Read More
A 27year old female with a history of Roux-en-Y gastric bypass, complicated by gastrojejunal anastomotic stricture resulting in Wernicke’s encephalopathy due to thiamine deficiency was admitted to our service for persistent tachycardia, palpitations, symptomatic orthostatic [....] » Read More
Pulmonary arteriovenous malformations (PAVM’s) are structurally abnormal vascular communications between pulmonary arteries and veins that range in size and complexity and contribute to an anatomic right-to-left shunt. They can present with varied symptoms including dyspnea [....] » Read More
Introduction/Background: Digital stethoscopes enhance the diagnostic power of auscultation through noise cancellation, waveform analysis, telehealth integration, and collaborative potential. Unfortunately, current products lack a cost-effective solution for synchronized listening [....] » Read More
Title : Should we continue to prescribe aspirin for patients with coronary artery disease?
Yochai Birnbaum, Baylor College of Medicine, United States
For years aspirin was considered an essential part of the treatment of patients with or at risk of coronary artery disease. However, more recent studies have shown that aspirin, even at low dose, does not improve outcomes when administered for primary prevention and is associated [....] » Read More
Title : Conditional probability utilization for the analysis of noninvasive cardiac testing
Timothy F Christian, Albert Einstein College of Medicine, United States
The use of multiple noninvasive tests in a patient for a specific question in cardiology is becoming more common. While it is expected that each new piece of test information will align, the reality is that each test carries strengths and weaknesses that generate a profile of acc [....] » Read More
Title : Normalizing effects of bacterial serum opacity factor on plasma lipids, tissues, and atherosclerosis
Corina Rosales, Houston Methodist Research Institute, United States
Although plasma HDL-C levels negatively correlate with atherosclerotic cardiovascular disease (ACVD), attempts to reduce ACVD risk by raising plasma HDL have disappointed. Thus, hypotheses about salutary HDL effects have shifted from higher-is-better to function-is-more-important [....] » Read More
Title : Screening for causes of secondary hypertension on hospital admission.
Syeda Anum Zahra, Imperial College NHS Trust, United Kingdom
Introduction: Although majority of patients have essential hypertension, secondary hypertension can also cause significant cardiovascular events. Secondary hypertension is defined as hypertension due to an identifiable cause and has a prevalence of 5-10%. European Society of Card [....] » Read More
Title : Heart failure: assessments and treatment prior to and during geriatric care
Marianne Reimers Wessberg, Karolinska Institute, Sweden
Background: Heart failure (HF) is globally the most common cause for admission to hospital for patients 65 years and older in high income countries. Research on HF has however often focused on younger patients. The aim of these studies was to analyze extent of investigation and t [....] » Read More
Title : The value of mixed and group-based exercise in stroke rehabilitation and secondary prevention: Results from a randomized cross-over trial in low-income settings
Nindorera Felix, UCLouvain, Belgium
Background: Post-stroke mobility deficits and physical inactivity are highly prevalent. Although physical activity has been shown to be effective for poststroke people, access to exercise training protocols is limited in community especially low-income settings. In addition, the [....] » Read More
Title : “Umbrella like” myocardial “no touch” surgical closure of the postinfarction posterior ventricular septal defect
Sasa Kacar, University Clinical Center of Serbia, Serbia
Post-infarction ventricular septal defect rupture (PIVSR) is rare but highly lethal complication of acute myocardial infarction. Even with well-established surgical treatment (David’s or Daggett’s technique), 30-days mortality is still high, more than 40%. The mo [....] » Read More
Title : The faces of post-streptococcal cardiac involvement in Paediatrics: A case series
Wilson Saputra Wijaya, Trisakti University, Indonesia
Group A Streptococcus (GAS) is a global burden, including in Indonesia, with long-term morbidity and mortality complications. The different response to nephrogenic and rheumatogenic strain makes concurrent post-streptococcal glomerulonephritis with acute rheumatic fever a rarity. [....] » Read More
Title : Assessment of strain imaging in the prediction of early Cancer Therapy-Related Cardiac Dysfunction (CTRCD) troponin and its correlation with serum biomaker (TROPONIN-I)
Dhulipalla Dharma Teja, NRI Medical College, India
Introduction: Cancer therapy-related cardiac dysfunction (CTRCD) is one of the side effects experienced by nearly one-tenth of cancer survivors. LVEF and GLS have been proposed as a marker to predict CTRCD. Recent studies also suggest assessment of cardiac biomarkers including tr [....] » Read More
Title : An unusual case of post-thrombolysis emergency Coronary Artery Bypass Graft surgery (CABG) with postoperative complication of hemothorax in a young patient
Anuja Waidande, Bharti Vidyapeeth Medical College and Hospital, India
We present a case of a 43-year-old man, a known case of hypertension, who was diagnosed with acute myocardial infarction for which he was given streptokinase (Fibrinolytic drug).He presented to the hospital with exertional dyspnoea and chest pain. Angiogram showed triple-vessel d [....] » Read More
Title : Assessment of risk factors, pattern and severity of CAD in semi-urban Indian women
Shivling Sanjay Swami, Bharti Vidyapeeth Medical College and Hospital, India
Introduction: It is an alarming observation that one third of all women in their fourth decade will develop coronary artery disease(1). Moreover, young women who develop coronary artery disease have a higher morbidity and mortality as compared to men of same age. (1,2) Traditiona [....] » Read More
Title : A conceptual paper on stakeholder collaboration aimed at addressing the psycho-social needs of women living with hypertension: Community development approach
Linda Shirindi, University of South Africa, South Africa
Stakeholder collaboration is significant to the contribution and improvement of psycho-social functioning and resilience of women living with hypertension. The purpose of the study was to explore and describe perceptions of stakeholders in addressing psycho-social needs of women [....] » Read More
Title : Surgical treatment of myxomas of the heart
Volodymyr Popov, Amosov National Institute of Cardiovascular Surgery, Ukraine
Purpose: To determine the possibilities of surgical treatment of myxomas of the heart (MH). Material and methods: In Institute for period from 1.01.1969 to 1.01.2020 957 patients (pts) with the verified primary tumors of heart were operated . The MH [....] » Read More
Title : Arch plasty of left atrium for moderate dilatation of left atrium during mv`s correction: Is it necessary?
Valery Boukarim, Amosov National Institute of Cardiovascular Surgery, Ukraine
Objective: To determined possibillities of left atrium (LA)`s reduction by original method of arch plasty of LA (APLA) during mitral valve replacement (MVR) for isolated mitral valve disease (MVD). Methods: During 2005 – 2021 yy. 454 adult patients [....] » Read More
Title : Mechanical valve for isolated mitral stenoses complicated massive thromboses of left atrium: Is it necessary?
Evgen Novikov, Amosov National Institute of Cardiovascular Surgery, Ukraine
Objective: To analyzed main problems in surgery of mitral valve diseases (MVD) complicated by left atrium`s massive thromboses (LAMT) (thromboses more than 1/3 of left atrium`s volume). Materials and Methods: 336 adult patients (pts) with MVD complicated LA [....] » Read More
Title : Plasty of left atrium for atriomegaly during mitral valve correction
Volodymyr Popov, Amosov National Institute of Cardiovascular Surgery, Ukraine
Objective: To determined possibillities of left atrium (LA)`s reduction by original method of triangular plasty of LA (TPLA) during valve`correction replacement. Methods: During 2005 – 2021 yy. 725 adult patients (pts) with MVD and LA`s at [....] » Read More
Title : Myocardial protection for isolated mitral valve replacement: Is retrograde applying of cardioplegia is better ?
Gurtovenko Alexey, Amosov National Institute of Cardiovascular Surgery, Ukraine
Objective: To present analysis of retrograde crystalloid cardioplegia during isolated mitral valve replacement (MVR) . Materials and Methods: During 2009-2020 y 529 patients (pts) with isolated pathology of mitral valve disease (MVD) were operated by MVR in departmen [....] » Read More
Title : Surgical outcome of post-infarction left ventricular free wall rupture
Chan Young Na, Dontan Hospital, Korea, Republic of
Background and objectives: Left ventricular free rupture is rare and one of the fatal complications after acute myocardial infarction. Early recognition and aggressive treatment is recommended. Methods: Between August 1999 and February 2023, eleven patients with ages [....] » Read More
Title : Rheumatic valve disease in pregnant women-An interesting case managed in two continents
Qazi Naeem Ur Rehman, Wirral University Hospital, United Kingdom
Rheumatic fever is the most common cause of mitral stenosis and carries a high degree of morbidity in pregnant females adverse foetal outcomes are associated with mitral stenosis in pregnancy. Pathophysiology, symptoms and diagnosis of rheumatic valve stenosis during pregnan [....] » Read More
Title : Plasmapheresis as a potential novel therapy to prevent cardiac fibrosis
Javier Lozano, University of the Philippines, Philippines
When a myocardial infarction (MI) takes place, a process of cardiac remodelling follows. This is necessary to resolve the reduced or blocked flow of blood into the stressed or dying cardiac tissue. This includes the formation of scar tissue and deposition of extracellular matrix [....] » Read More
Title : Metastudy of potential key genes associated with cardiac fibrosis after acute myocardial infarction from published microarray data in a mouse model
Al James A Manua, University of the Philippines, Philippines
In this study, we investigated the shared key genes, pathway networks, and transcription factors (TFs) associated with Cardiac Fibrosis following Acute Myocardial Infarction (AMI) in mouse models. Gene expression profiles of AMI and the sham-control group were obtained from the [....] » Read More
Title : Simplified Method for the simultaneous isolation of viable cardiomyocytes and nonmyocytesfrom the adult mouse heart
Mariel Lizbeth Joy Agsaoay, University of the Philippines, Philippines
Cardiovascular diseases (CVDs) have remained the leading cause of global mortality. Of these, one of the main events leading to death is myocardial infarction (MI), followed by cardiac fibrosis. To better understand the disease and its development, various techniques [....] » Read More