Title : Exercise training improves diastolic function in IHD patients.
Abstract:
Purpose: The purpose of this study was to investigate the effect of exercise training on exercise tolerance and left ventricular diastolic function and structure in patients with chronic cardiac ischemia.
Methods: Eighty-eight patients with cardiac ischemia and diastolic disfunction who were receiving appropriate treatment according to the guidelines were randomly divided into exercise training along with usual care (n=60) or usual care alone (n = 28) in a random ratio of 2:1. Left ventricular diastolic function and exercise tolerance were evaluated before and after each intervention.
Results: Exercise tolerance and diastolic function improved with exercise training in, while they remained unchanged after usual care alone. In patients with grade 3 diastolic dysfunction , exercise training decreased the E/A ratio and increased DT, both of which were unchanged after usual care alone. In the remaining patients (diastolic disfunction grade 1,2), exercise training also improved mitral inflow patterns.
Conclusion: These results show that exercise training can improve the pattern of cardiac diastolic function independently of the level of baseline left ventricular diastolic dysfunction.
