HYBRID EVENT: You can participate in person at Madrid, Spain or Virtually from your home or work.

5th Edition of Cardiology World Conference

September 5-7, 2024 | Madrid, Spain

September 05 -07, 2024 | Madrid, Spain
Cardio 2023

Aditi Parulkar

Aditi Parulkar, Speaker at Cardiovascular Conference
Parulkar Hospitals, India
Title : The role of epicardial adipose tissue in clinical cardiology


Epicardial adipose tissue is an area of multidisciplinary interest and tremendous potential for upcoming research. It is composed of adipocytes as well as inflammatory cells, nervous cells, vascular cells and immune cells. It has multiple protective functions and has functional interactions with the cardiac tissue due to shared circulation and lack of anatomical barrier. EAT contributes to disease progression by a variety of mechanisms from immune response, inflammation, oxidative response, endothelial damage, lipid accumulation. In cardiovascular diseases like CAD, Atrial fibrillation, Heart failure and Diabetes mellitus EAT promotes atherogenesis, arrhythmias, cellular fibrosis and apoptosis. EAT can be assessed by 2D Echocardiography, Cardiac MRI and contrast or non-contrast enhanced CT. Localisation of regionally distributed EAT in left atrial and pericoronary has immense scope in predicting the associated cardiovascular risk. A higher EAT volume is associated with a Coronary artery calcium score greater than 10 which can predict atherosclerosis risk. EAT volume and thickness is also higher in chronic Atrial fibrillation patients compared to patients with paroxysmal Atrial fibrillation. In addition, EAT is a novel target for cardiometabolic drugs with effects on GLP1R and SGLT2 receptors. EAT expresses Angiotensin Converting Enzyme 2 (ACE2) that serves as an entry receptor for SARS-CoV-2 and functions as a reservoir for the virus. To conclude, EAT presents tremendous promise in risk prediction and clinical application. The possibility of cardiometabolic modulation provides an avenue for modification of cardiovascular risk. The research on this topic is still in its beginning stages and its potential is yet to be demonstrated in clinical decision making. 
Audience Take Away Notes
• This presentation discusses the role of Epicardial Adipose tissue with the physiologic and pathological properties of    EAT and its implication in cardiovascular disease and application in risk stratification
• We discuss imaging techniques to measure it clinically and assess cardiovascular risk while also understanding the significance of regional distribution of EAT and how Coronary and Left atrial EAT affect cardiovascular diseases
• We discuss how it can be a potential therapeutic target for cardiometabolic medications modulating adipose tissue
• We also shine light on the correlation between type 2 Diabetes mellitus and high levels of epicardial adipose tissue    and its role in COVID-19 related cardiac syndrome


Dr. Aditi Parulkar obtained her MBBS degree from People’s College of Medical Sciences and Research Centre, India in 2020. She is currently working as a
research associate at Maimonides Medical Centre, Brooklyn, New York. During the formative years of her medical education, Dr. Parulkar had the opportunity to complete her Summer Undergraduate Visitor Program at Stanford University in 2016. Dr. Parulkar has been actively practicing medicine both in India and the
United States, gaining invaluable clinical experience while continuously expanding their skill set in clinical research. With first hand exposure to diverse healthcare
systems, Dr. Parulkar aims to contribute to the ongoing evolution of healthcare and enhance patient outcomes.