Title : Role of Myocardial Perfusion Imaging in the diagnosis of Coronary Artery Disease
Millions peoples both man & women are worldwide dying due to heart attack each year. When a blood clot totally blocks the artery, the heart muscle becomes starved for oxygen. Within a short time, death of heart muscle cells occurs, causing permanent damage, called heart attack. Myocardial infarction (MI), is permanent damage to the heart muscle. The heart muscle requires a constant supply of oxygen-rich blood to nourish it. Heart attack and heart disease is the leading cause of death in whole world. Currently, there is major change have been seen in the diagnosis and treatment of coronary heart disease. Nuclear Cardiology is playing very significant role in accurate diagnosis of heart disease and in the assessment, extent and the prediction of outcomes in the setting of coronary artery disease.
Aim: To assess the role of myocardial perfusion imaging in evaluation of coronary artery disease.
Materials and methods: The study retrospectively analyzed 23 myocardial perfusion imaging scans in a newly established Nuclear Medicine centre, of which 8 were exercise stress testing, 8 were pharmacological stress testing with Adenosine and remaining 7 were rest perfusion imaging. The cohort included 16 males belonging to the age group 40 to 70 years and 7 females of age group 37 to 69 years. The study was conducted with Tc-99m MIBI and images were acquired using NM 670 DR SPECT/CT machine by GE Healthcare.
Results: 03 patients who underwent exercise stress testing showed stress inducible ischemia. 02 patients underwent coronary angiography and subsequent stenting. Another patient with chronic total occlusion of left anterior descending artery was advised for CABG. Another patient was kept on follow up as the territory of involvement was less than 10 percent. 08 patients underwent pharmacological stress testing, 06 showed fixed perfusion defects (cases of recent myocardial infarcts), 02 were normal. 02 out 07 patients who underwent myocardial rest scan showed viability in infarct territory.
Conclusion: Myocardial perfusion imaging is very beneficial in providing timely intervention in patients with cardiovascular morbidity.