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October 24-25, 2019 | Tokyo, Japan

Mekhman N Mamedov

Oral Speaker at Cardiology Conferences 2019- Mekhman N Mamedov
Mekhman N Mamedov
National Research Center for Preventive Medicine, Russia
Title : Relationship of glycemic status, arterial hypertension and macrovascular complications: results of a multicenter cohort study

Abstract:

528 patients with T2DM, aged 30–69 years (30.5% men, 69.5% women) were included in the clinical and epidemiological study. Values of glycohemoglobin ≥7% were regarded as diabetic decompensation.

All patients were conducted a survey, clinical examination, measurement of atropometric and hemodynamic parameters, ECG at rest and ECHO CG. In addition, we determined the carotid intima-media thickness (IMT), the ankle-brachial index, as well as the form and extent of blood flow disorders in the vessels segments of the lower extremities. Cardiovascular diseases are verified by survey, clinical examination and medical records.

Results: With inadequate control of diabetes, AH was more common (83.5%), and the severity of AH was significantly more significant (p = 0.023), ECG and EchoCG showed signs of left ventricular hypertrophy. A prolonged antihypertensive therapy was taken by a small proportion of patients, in most cases in the form of a course of treatment and during a rise in BP. In this group of patients, more angina was detected (according to a survey - 7%), ECG signs of CAD (26.7%), EchoCG signs of aortic atherosclerosis (46.7%), myocardial infarction (6.1%) and its ECG signs (37 , 1%), as well as hypokinesis (33.3%) and akinesis (21.0%). Poor glycemic control was associated with frequent occurrence of rhythm disturbances (22.2%), CHF (40.0%), diastolic (54.9%) and systolic dysfunction (20.6%). Stroke (5.2%), severe degrees of stenosis of the carotid arteries increased with decompensation of diabetes, an increase in the IMT was also noted. In the lower limbs, the main type of blood circulation was determined, severe stenosis increased at the periphery, impaired blood flow was noted mainly in the subcompensation stage, and in the popliteal ankle segment also in the decompensation stage.

Conclusion: In cases of the inadequate glycemic  control in patients with T2DM, macrovascular complications and hypertension were recorded more frequently. This circumstance indicates increased glycemic control and prevention of CVD.

Biography:

Professor Mehman Mamedov graduated from the I.M. Sechenov Moscow Medical Academy in 1993.  He continued his medical education as a cardiology intern at the Medical Centre for the President of the Russian Federation, at the Central Clinical Hospital.

Dr Mamedov holds a PhD degree (1997) from the National Research Centre for Preventive Medicine. His thesis was entitled, “The components of the metabolic syndrome in arterial hypertension patients”. In 2001, he wrote a higher doctorate thesis on, “The clinical and biochemical peculiarities and approaches to the pharmaceutical management of the metabolic syndrome”.

Under Dr Mamedov’s supervision, 9 PhD and 1 higher doctorate theses were achieved.

Today Dr. Mamedov is Head of the Laboratory for Interdisciplinary Approaches on the Prevention of Chronic Non-communicable Diseases at the National Research Centre for Preventive Medicine; Vice-President of the Cardioprogress Foundation, and Deputy Chief Editor of the International Heart and Vascular Disease Journal. He is also  member of the Board of the Russian Society of Cardiology and Head of the Diabetes and CVD Section, member of the editorial board of the journals Cardiology and Cardiovascular Prevention and Therapy and the organizer of the annual International Forum of Cardiology and Internal medicine  in Moscow and 4 regional conferences.

Dr Mamedov M. is an author of more than 300 scientific works, including 14 monographs and books, some of which were published in English. His Hirsch index is 28, Scopus and Web of science index -5.   

The scientific interests of Dr Mamedov encompass cardiometabolic disorders, disorders of lipid metabolism, men's health problems, prognosis and correction of cardiovascular risk, early markers of atherosclerosis, prediabetes and diabetes, epidemiology of cardiovascular disease and chronic non-inflectional diseases.