Title : Echocardiography guided percutaneous closure of patent foramen ovale with biodegradable device
Abstract:
PFO is one of the most common congenital heart diseases and fluoroscopic percutaneous closure devices based on non-degradable alloys have been widely used in clinical application and saved numerous patients but some developed countries using biodegradable closure devices under fluoroscopy and may offer some advantages such as fewer complications, acceptable for biocompatibility and particularly temporary existence and later on convert to a native tissue by endothelization, In Fuwai hospital Chinese academy of medical science, we used degradable device for PFO closure without fluoroscopy (echocardiography guided).
A 48 years old woman had headache 3 years ago her brain MRI showed cerebral infarction, TEE showed PFO but no history of pneumonia, heart failure, cyanosis and strokes. TEE shows the middle part of Intra Atrial Septum bulge toward right Atrium With PFO separated obliquely like a tunnel with a length about 18mm and width of 2.6 mm but otherwise normal chambers and valves function.34mm×34mm biodegradable device (Lepu Medical Technology, Beijing, China?selected for closure. Through Trans-femoral access PFO successfully closed, there were no residual shunt and AV valves functioning well on post procedure echocardiography. Patient shift to the ward and after two days patient discharged with stable condition. The procedure is done under simple echocardiographic guidance without fluoroscopy. The Pan (Percutaneous and non-fluoroscopy procedure is safe and economical, Pan Procedure not only protect patients from radiation it can also protect from contrast worse effects on the kidney and allergy to contrast.
This study conducted with approval from the ethic committee of Fuwai hospital Chinese academy of medical sciences and national center for cardiovascular center, written informed consent to publish the clinical details.
Key words: PFO, percutaneous, echocardiography guided, biodegradable device
