Title : Evaluation and prediction of cardiovascular risk prognosis in type II diabetic patients by evaluating glycosylated hemoglobin and cardiac troponin
Abstract:
Introduccion: Diabetes is a major comorbidity for heart failure and is more common than myocardial infarction with an increased risk of more than 50% in cardiovascular disease. Recently, high-sensitivity cardiac troponin T (hs-cTnT) has been shown to be associated with the incidence of CVD. Elevated glycated hemoglobin (HbA1c) is considered an independent risk factor for acute coronary syndrome in patients with diabetes mellitus.
Method: 12 control patients and 12 patients with type II diabetes were studied to evaluate residual cardiovascular risk prognosis. The levels of cTnIus levels and % HbA1c were analyzed and compared in the assessment of cardiovascular risk. CVR: (0 to 1), closer to 1 the better prognosis.
Results: Controls showed a prognosis of increased cTnI (294.1 to 352.2 ng/ml) and HbA1c (5.46 to 5.51%) with a CVR (0,65 to 0,62) compared to diabetes patients (288,8 to 359,2 ng/ml) and HbA1c (7,91 to 8,20 %) with CVR (72 to 68) in a 3-month period. ANOVA II post test Sidak showed showed an increase significant difference between diabetic and control patients regarding cardiovascular risk (0,74 ± 0,03 vs 0,64 ± 0,03), P= 0.024.
Conclusion: % HbA1c is a more efficient marker in the prediction of cardiovascular risk compared to cTnI in the long term.
