HYBRID EVENT: You can participate in person at Valencia, Spain or Virtually from your home or work.

4th Edition of Cardiology World Conference

September 18-20, 2022 | Hybrid Event

September 18 -20, 2023 | Valencia, Spain
Cardio 2023

Bijay Patni

Bijay Patni, Speaker at Cardiology Conference
Diabetes Wellness Care, India
Title : Prevalence of hyperuricemia in hypertensive Indian population

Abstract:

Background & Objective

The prevalence rate of Hyperuricemia is comparatively higher in Asian countries than in the western regions. Hypertensive patients with co-existing Hyperuricemia (HU) are at greater risk of uncontrolled HTN, metabolic syndrome and its complications. This study aims to determine the prevalence of hyperuricemia in hypertensive individuals from the major geographical regions across India.

Methods

A cross-sectional, multicentric, observational study conducted in primary and secondary care centres from urban areas across different regions in India. Primary inclusion criteria were either history of hypertension or patients with SBP ≥140 mm Hg and DBP ≥ 90 mm Hg. A structured google form was circulated among the participating healthcare practitioners from various participating centres to record the demographic, clinical and biochemical parameters of patients visiting the respective centres. The data was consolidated and analysed used using Microsoft excel. Screening for HU among individuals with HTN was based on two criteria 1) self-reported diagnosed history of hyperuricemia or 2) based on serum uric acid levels >7 mg/dL for men or serum uric acid >6 mg/dL for women.  The data were analyzed and represented using GraphPad Prism version 9.

 

Results

A total of 1528 study individuals out of the total study population were hypertensive from 12 participating centres across different regions in India. The mean age of the study participants was 57.4 ± 10.5 years. The total prevalence rate of HU among individuals with HTN is 22.5% (N=345). Male to female ratio was 1:1. Gender-wise analysis indicated that 51.5% (177) of the males and 48.5%  (168) of the females had HU. Among the patients with HTN and HU, 75% were overweight with a BMI ≥ 25kg/m2. The region-wise prevalence rate HU are North: 17.4% (60); South:18% (62); Central:12.2% (42); East:29.6% (102) and West:22.9% (79). 

Conclusion

India's overall HU prevalence rate (22.5%) was comparable to that in other Asian countries (10-30%). However, the prevalence of HU in HTN patients varies between different regions of India (12.2-29.6%). Results from the participating centres from the urban setting indicated that the eastern region had the highest HU prevalence (29.6%), and the central region had the lowest HU prevalence rate (12.2%).  The varying prevalence rate can be attributed to the diversity in geographical factors, genetic background or (family history of HU), sociocultural habits and metabolic perturbations. Understanding this prevalence rate diversity can help strengthen the HU prevention measures to improve the quality of life.

Key Words – Hyperuricemia prevalence, hypertension, metabolic syndrome, diabetes.

Background & Objective

The prevalence rate of Hyperuricemia is comparatively higher in Asian countries than in the western regions. Hypertensive patients with co-existing Hyperuricemia (HU) are at greater risk of uncontrolled HTN, metabolic syndrome and its complications. This study aims to determine the prevalence of hyperuricemia in hypertensive individuals from the major geographical regions across India.

Methods

A cross-sectional, multicentric, observational study conducted in primary and secondary care centres from urban areas across different regions in India. Primary inclusion criteria were either history of hypertension or patients with SBP ≥140 mm Hg and DBP ≥ 90 mm Hg. A structured google form was circulated among the participating healthcare practitioners from various participating centres to record the demographic, clinical and biochemical parameters of patients visiting the respective centres. The data was consolidated and analysed used using Microsoft excel. Screening for HU among individuals with HTN was based on two criteria 1) self-reported diagnosed history of hyperuricemia or 2) based on serum uric acid levels >7 mg/dL for men or serum uric acid >6 mg/dL for women.  The data were analyzed and represented using GraphPad Prism version 9.

 

Results

A total of 1528 study individuals out of the total study population were hypertensive from 12 participating centres across different regions in India. The mean age of the study participants was 57.4 ± 10.5 years. The total prevalence rate of HU among individuals with HTN is 22.5% (N=345). Male to female ratio was 1:1. Gender-wise analysis indicated that 51.5% (177) of the males and 48.5%  (168) of the females had HU. Among the patients with HTN and HU, 75% were overweight with a BMI ≥ 25kg/m2. The region-wise prevalence rate HU are North: 17.4% (60); South:18% (62); Central:12.2% (42); East:29.6% (102) and West:22.9% (79). 

Conclusion

India's overall HU prevalence rate (22.5%) was comparable to that in other Asian countries (10-30%). However, the prevalence of HU in HTN patients varies between different regions of India (12.2-29.6%). Results from the participating centres from the urban setting indicated that the eastern region had the highest HU prevalence (29.6%), and the central region had the lowest HU prevalence rate (12.2%).  The varying prevalence rate can be attributed to the diversity in geographical factors, genetic background or (family history of HU), sociocultural habits and metabolic perturbations. Understanding this prevalence rate diversity can help strengthen the HU prevention measures to improve the quality of life.

Key Words – Hyperuricemia prevalence, hypertension, metabolic syndrome, diabetes.

Biography:

Dr. Bijay Patni, a Consultant Physician and Cardio Diabetologist, graduated in MBBS from NRS Medical College & Hospital, Kolkata in 1990 (Medical Regn No: 49475 of WBMC). He holds several diplomas and post graduate diplomas in diabetology and cardiology from various reputed universities. He is currently working as a HOD at Diabetes Wellness Care, Kolkata. He is a founder of Diabetes Research And Welfare Association (DRWA) and Executive Committee member of the Indian society of Hypertension, Indian society of Chronomedicine, Clinical Cardio & Diabetology Society of India. He is a faculty at National and local conferences like RSSDI, DIPSI, DRWA, BPCON, ACP, CCDSICON, RSSDI Jharkhand & Bihar CHAPTERS, “Hello diabetes”, Bihar Diabetic Association, Tripura IMA, API Jharkhand, CARDIABCON, ISCM, Dialogues in Diabetes, Evastride, Diabetes India, etc. He has been a regular speaker for various pharmaceutical houses like Sanofi, Novo Nordisk, Glenmark, Zydus, Sun, Abbott, Novartis, Eli-Lily, BI, MSD, J B Chemicals, etc. He has published several poster Presentations, abstracts, and chapter publications in national and international conferences

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