Title : Heart rate variability in patients with atrial fibrillation depending on previous COVID-19 infection
Abstract:
Introduction: It is known that the balance between sympathetic and parasympathetic regulation of the heart is characterized by indicators of heart rate variability (HRV). In patients with paroxysmal and persistent forms of atrial fibrillation (AF), HRV values ??may differ from normal values. The purpose of our study was to evaluate indicators of HRV in patients with AF depending on the past coronavirus infection (CI). Material and methods of research: We examined 131 patients aged 62.5 + 0.09 years with paroxysmal or persistent forms of AF in sinus rhythm. 93 people had a history of an average of 6.2 + 0.5 months ago of COVID-19 infection. They made up the 1st group of examined patients. The remaining 38 patients did not have a history of this infection. They constituted the 2nd group of the study, which was the control group. The specific number of patients with paroxysmal and persistent AF in the groups was comparable. 24 –h Holter monitoring ECG and indicators of HRV were performed according to standard methods. Results of the study: We found that in the group was a significant difference in minimum heart rate per day (HRD) (50.3 + 1.4 beats/min and 45.5 + 1.4 beats/min in groups 1st and 2nd, p<0.01) and maximum HRD (113.0 + 2.0 beats / min and 106.1 + 1.72 beats / min in the 1st and 2nd groups, p<0.01), as well as a trend towards statistical significance between the average HRD (71.2 + 1.6 beats/min and 65.7 + 2.9 beats/min in the 1st and 2nd groups). Significant confidence was also obtained for such indicators between groups "1" and "2" in such indicators of HRV as - SDANN (102.7 + 2.33 and 151.7 + 1.23 ms, p<0.001), SDNN (124, 3 + 4.06 and 181.3 + 4.83 ms, p<0.001), and RMSSD (100.4 + 4.57 and 173.2 + 13.51 ms, p<0.001). Conclusion: In patients with AF, after undergoing CI, was a change in the autonomic regulation of the heart rhythm towards sympathetic activation, and as a result, an increase in the electrical instability of the atria. What will audience learn from presentation Balance between sympathetic and parasympathetic regulation of the heart, which characterized by indicators of heart rate variability (HRV) in patients with paroxysmal and persistent forms of atrial fibrillation (AF) was studied. Shown, that in patients with AF, after undergoing CI, was a change in the autonomic regulation of the heart rhythm towards sympathetic activation. It is important to pay attention to this, because a change in HRV indicators usually indicates the readiness of the heart for arrhythmias in general and AF specifically.
