Abstract:
Aim. To assess the predicted ten-year survival rate and the risk of cardiovascular complications in adult population in the Vladimir region of the Russia.
Material and methods. A cross-sectional population study included 1200 men and women aged 30-69 years from 5 cities of the Vladimir region. The response to the study was not <80%. In total, 1004 people completed the study. Of these, 346 are men (34.5%) and 658 are women (65.5%). The respondents were interviewed using a standard questionnaire, which includes information on socio-demographic indicators, behavioral risk factors, the presence of somatic diseases, registration of drugs taken and an assessment of psychosomatic status. Instrumental and laboratory studies were performed, included in the first stage of the dispensary examination. To assess the risk of cardiovascular diseases, the European SCORE scale was applied. To assess the 10-year survival rate of individuals, the Charlson comorbidity index was used.
Results. Hypertension was detected in 38% of men and 43% of women. Ischemic heart disease among men is registered three times more often than women: 15% and 5% (p <0.0001). Other chronic non-communicable diseases such as diabetes mellitus, chronic obstructive pulmonary disease and malignant tumors were identified separately in no more than 5% of cases. 67% of women had low to moderate cardiovascular risk (CVR). 19% of men had high and 10% very high CVR, which turned out to be higher than in women (6% and 0%). The prevalence of the combination of the two diseases was 32.6%. Among men, this indicator is 36.7%, while among women it is 10% less, it was found in every fourth participant in the study (27%) (p = 0.002). The combination of three diseases among men was detected in 12%, and among women it was detected in 5.9% of cases (p <0.001). A short ten-year survival rate (21% and <5%) according to the Charlson index was found in less than 10% of men and women. The largest number of respondents had 90% and 77% ten-year survival rates.
Conclusion. In the unorganized population of adults, high and very high CVR was found in every fourth man and only in every 16 women. A short ten-year survival rate according to the Charlson index was found in every tenth respondent, while every second participant had an average ten-year survival rate. The comorbidity of somatic diseases with low and average ten-year survival requires complex interventions and regular monitoring.
Key words: prevalence, comorbidity of chronic non-communicable diseases, cardiovascular risk, Charlson's index, adults.
Biography:
Professor Mehman Mamedov graduated from the Moscow Medical Academy named after I.M. Sechenov in 1993. He continued his medical residency at the Central Clinical Hospital of the Presidential Administration of the Russian Federation. In 1997 Dr. Mamedov received his PhD degree in the National Research Center for Preventive Medicine of the Ministry of Healthcare of the Russian Federation for research titled "Metabolic syndrome components in patients with arterial hypertension". In 2001 he wrote his doctoral thesis on "Clinical and biochemical features of metabolic syndrome and its pharmacological management". He has been working in the National Medical Research Center for Therapy and Preventive Medicine for 26 years, beginning as a researcher and eventually becoming the head of the scientific laboratory.
He is the author of 400 scientific works, 16 monographies in Russian, 4 monographies in English and 3 patents. Hirsch Index: RSCI — 36, Scopus — 6, Web of Science — 6. Under Dr. Mamedov’s supervision, 10 PhD and 1 doctoral thesis have been defended. Recently, Professor Mamedov M.N. has initiated 12 research projects, including some presented at the congresses of the American College of Cardiology, the European Society of Cardiology, the World Heart Federation, as well as at other international and national scientific events.
Professor Mamedov M.N. annually gives lectures in Russia and other countries. His research interests include: cardiometabolic disorders, lipid metabolism disorders, male health issues, cardiovascular risk assessment and correction, early markers of atherosclerosis, prediabetes and diabetes mellitus, risk factors and cardiovascular disease epidemiology, cardio-oncology, and comorbidities in internal medicine.
Dr. Mamedov is the editor-in-chef of the "International heart and vascular disease journal", member of the editorial board of the "Cardiology" and "Cardiovascular Prevention and Therapy" journals, head of the Department of Secondary Prevention of Chronic Noncommunicable Diseases of the National Medical Research Center for Therapy and Preventive Medicine, and President of the Cardioprogress Foundation.
Professor Mamedov M. was an executive secretary of the Russian National Congress of Cardiology for 6 years, organizing regional and national scientific conferences. He is one of the founders of the International Forum of Cardiology and Internal Medicine, which has been held annually at the Russian Academy of Sciences since 2012. He has letters of appreciation from the head of the Republic of Ingushetia, ministers of health of the Russian Federation, Uzbekistan, Tajikistan, Belarus, the Chechen Republic and the presidents of the Turkish Society of Cardiology, the Association of Internists of Kazakhstan and the National Health League. In 2019, he was awarded with V.D. Shervinsky medal by the President of the Russian Scientific Medical Society of Internal Medicine for his contribution to the development of medical science.
