Title : Circadian rhythm of Blood Pressure and its related factors in patients with Hypertension
Abstract:
Circadian rhythms are known to affect human body in various ways and blood pressure is not an exception; normally blood pressure drops during the night.
Hypertension is a common treatable and controllable disease that could lead to fatal complications via different mechanisms.
Having those said in mind, we aimed to determine the abnormality of circadian rhythms in hypertensive patients.
183 individuals having hypertension and over 30 years old were selected and studied on, with the data gathered from checklist and 24-hour blood pressure monitoring. Ambulatory blood pressure monitoring (ABPM) was chosen because it is the best diagnostic method for hypertension considering errors in common diagnostic errors that is done by individual measurements.
Patients were divided into two categories; dipper and non-dipper. The dipper group had a reduction in blood pressure during a sleep and contrariwise. Most patients (77%) had non-dipper blood pressure pattern.
Previous studies have shown the risk of developing sleep problems, metabolic syndrome, cardiovascular disease and stroke among individuals with abnormal circadian rhythm of blood pressure.
We suggest lowering of nocturnal blood pressure based on ABPM results using diuretics -either alone or in combination with other drugs; because they tend to lower night-time pressure and by that means, reducing the risk of these disorders in patients with non-dipper HTN.
What will audience learn from your presentation?
- Educate patients about normal circadian rhythm of blood pressure and associated risks
- Assess hypertensive patients for nocturnal rise in blood pressure
- Lower the nocturnal blood pressure preferably using combination drug therapy
- Diuretics are suggested for night time blood pressure control due to their role in preventing heart failure
