Title : A rare case of symptomatic bradycardia secondary to Aripiprazole on 61-yo Male with Bipolar disorder type 1: Case report and literature review
Abstract:
We present a case of a 61-year-old male with a medical history of bipolar disorder type I, diagnosed 1 year ago, recently started on aripiprazole. Presented to the emergency department (ED) complaining of intermittent episodes of dizziness that initiated after his second dose of intramuscular (IM) aripiprazole, but worsened 3-day prior. In ED was found to have bradycardia of 44 beats/minute, normotensive, and pulse oximetry of 98% on room oxygen. An electrocardiogram showed sinus bradycardia of 44 bpm with QT of 410 msec. Cardiology evaluation was unremarkable. The psychiatric evaluation suggested discontinuation of Aripiprazole, with subsequent improvement of heart rate and resolution of bradycardia.
What will audience learn from your presentation?
- Explain the mechanism of action of the second generation of antipsychotics and their effects on the cardiovascular system.
- Create awareness of the medical community's potential causes of symptomatic bradycardia in patients with antipsychotic treatment.
