Title : Conotruncal defects: congenital heart disease with the highest mortality rate in the neonatal period
Abstract:
Congenital heart diseases (CHD) are the most common congenital malformations, with an incidence of about 1 per 100 at live birth in China. Conotruncal defects (CTD) are a heterogeneous type of CHD, and little is known about their etiology. They are a group of diseases characterized by abnormal development and separation of the outflow tract in the embryonic period, which are the type of congenital heart disease with the highest mortality in the neonatal period, and the untreated mortality rate is as high as 78%. CTD usually require catheter-based or surgical treatment early in life, but the mortality rate remains high.
