Professor John Horowitz trained in Medicine in Adelaide, with subsequent clinical and research training in Cardiology and Clinical Pharmacology at the University of Melbourne. From 1980 to 1982 he was a postdoctoral research fellow at the Brigham and Women’s Hospital, Harvard University, Boston. In 1988 he was appointed as Director of Cardiology at the Queen Elizabeth Hospital, Adelaide, and Professor of Cardiology, Adelaide University. His major research interests centre on the pathogenesis and potential treatment of various forms of cardiovascular disease, including myocardial ischaemia, heart failure, atrial fibrillation, aortic valve stenosis and takotsubo syndrome. Among his specific pharmacological/therapeutic interests are the potential utilities of the cardiac metabolic manipulator perhexiline and the antioxidant N-acetylcysteine.