Title : Home external defibrillation or pacing-the only strategy that can reduce sudden cardiac death
Abstract:
Sudden Cardiac Death (SCD)-caused by Ventricular Fibrillation (VF) or standstill-is one of the biggest unmet need in public health: It is unpredictable and occurs in about 1000 persons/day in US and Europe alone with very poor survival. Since survival drops by 10% for every minute delay-ambulances or high-cost public AED’s are too late to save them and defibrillation or pacing should be used immediately, at home or office - where it occurs (in 80% of cases).
Our breakthrough technology device modifies by computer the sinusoidal alternating electrical current from the mains to a biphasic defibrillatory wave or to a pacing stimulus in case bradycardia or standstill-affordable to every household. Two animal experiments proved its safety and feasibility: In the first: Defibrillation of stable VF in 5 pigs was applied by our device and compared to a standard AED. Repeated defibrillation was successful by both devices and thresholds were found to be similar. The second experiment used six rats, following infarct by coronary closure-VF was induced with similar external defibrillation and in addition-our device only used external pacing successfully achieved in all, at a heart rate above their rate, for an unlimited time before and after defibrillation.
In future-pulse sensor watches will detect SCD and alert by bluetooth nearby people to use our device-immediately. We conclude that our breakthrough technology is feasible and at a much lower cost-more effective than that of the standard AED. This should be used to prevent SCD occurring at home/office and will revolutionize resuscitation outcome.
