HYBRID EVENT: You can participate in person at Paris, France or Virtually from your home or work.

2nd Edition of Cardiology World Conference

September 17-18, 2021 | Paris, France

September 17-18, 2021 | Paris, France

James Ratcliff

Keynote Speaker for Cardiology Conference 2021- James Ratcliff
James Ratcliff
Rowpar Pharmaceuticals, USA
Title : Inflammation and oral pathogens as determinants of Hypertension


Chronic infections are regarded as risk factors to coronary heart disease and stroke. One such chronic disease, gum disease, is at epidemic proportion among the adult population.   Periodontitis has been shown to be linked to endothelial dysfunction. It has also been linked to hypertension, although it is inconclusive as to whether periodontal therapy alone can reduce blood pressure. Gram-negative anaerobes enter into the bloodstream after various stimuli, such as tooth brushing and chewing and periodontal treatment. Several of these are known to deplete nitric oxide (NO) bioavailability, and lower NO bioavailability increases vasculature injury and hypertension.

The relationship between inflammation, oral pathogens and hypertension is reviewed from the perspective of preventative care – both professional preventive care and home oral care. Findings of research reviews suggest that oral health assessment together with effective home oral care may improve both the patients’ quality of life and the management of hypertension.  Specific criteria are put forward to improve professional and home oral care in support of the lowering of the incidence of hypertension.


James L. Ratcliff is Chairman of the Board and CEO of Rowpar Pharmaceuticals, Inc., Scottsdale, AZ, maker of the Cl?SYS brands of oral care products. In 2017 and 2018, Rowpar was cited by Corporate Livewire as innovative leader in oral care for North America. In 2014, Rowpar received the U.S. Small Business Administration’s Exporter of the Year Award.  1989-2000, Dr. Ratcliff served as senior research scientist, professor and director, Center for the Study of Higher Education at the Pennsylvania State University.  1979-1989, Dr. Ratcliff was professor and program head for higher education at Iowa State University.  Dr. Ratcliff is author of 120 articles, books, book chapters, is co-inventor on over 40 patents and patents pending.  He is active member of the Arizona Biotechnology Assn., American Academy of Oral and Systemic Health, and the International Association for Dental Research. He holds a Ph.D. in Higher Education from Washington State University, a M.A. in History from Washington State University, and a B.A. from Utah State University.